Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, Weinberg DE†, Weissman JS† (2017). CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science 357:414–7.
Osuna BA, Howard CJ, KC S, Frost A†, Weinberg DE† (2017). In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing. eLife 6:e27949.
Weinberg DE†, Gross JD (2016). Molecular biology: Messenger RNAs marked for longer life. Nature 541:293–4.
Di Santo R, Aboulhouda S, Weinberg DE† (2016). The fail-safe mechanism of post-transcriptional silencing of unspliced HAC1 mRNA. eLife 5:e20069.
► Check out the related eLife Insight article, "Silence without stress" by David Young & Nick Guydosh, that summarizes our findings!
Odegaard JI, Lee MW, Sogawa Y, Bertholet AM, Locksley RM, Weinberg DE, Kirichok Y, Deo RC, Chawla A (2016). Perinatal Licensing of Thermogenesis by IL-33 and ST2. Cell 166:841-54.
Weinberg DE*†, Shah P*, Eichhorn SW, Hussmann JA, Plotkin JB, Bartel DP (2016). Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation. Cell Reports 14:1787-99.
Presnyak V*, Alhusaini N*, Chen Y-H*, Martin S, Morris N, Kline N, Olson S, Weinberg D, Baker KE, Graveley BR, Coller J (2015). Codon optimality is a major determinant of mRNA stability. Cell 160:1111–24.
Nakanishi K*, Weinberg DE*, Bartel DP, Patel DJ (2012). Structure of yeast Argonaute with guide RNA. Nature 486:368–74.
Bernstein DA*, Vyas VK*, Weinberg DE, Drinnenberg IA, Grisafi PG, Bartel DP, Fink GR (2012). Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation. Proc Natl Acad Sci USA 109:523–8.
Weinberg DE*, Nakanishi K*, Patel DJ, Bartel DP (2011). The inside-out mechanism of Dicers from budding yeasts. Cell 146:262–76.
Drinnenberg IA*, Weinberg DE*, Xie KT*, Mower JP, Wolfe KH, Fink GR, Bartel DP (2009). RNAi in budding yeast. Science 326:544–50.
Sim S, Yao J, Weinberg DE, Niessen S, Yates III JR, Wolin SL (2012). The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the nonconding Y3 RNA. RNA 18:100–10.
Sim S, Weinberg DE, Fuchs G, Choi K, Chung J, Wolin SL (2009). The subcellular distribution of an RNA quality control protein, the Ro autoantigen, is regulated by noncoding Y RNA binding. Mol Biol Cell 205:1555–64.
* indicates equal contributions
† indicates corresponding author